Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep1028 | Pituitary and Neuroendocrinology | ECE2024

Neurosteroids in human pituitary adenomas

Hatipoglu Esra , Akpinar Ebubekir , Erkan Buruc , Yalcinkaya Selahattin , Aksoy Şeyma , Burhan Sebnem , Gunaldı Omur , Tanriverdi Osman , Niyazoğlu Mutlu

Neurosteroids refer to hormones with a steroid structure and, their synthesis pathways are identical to those of traditional steroids. However, neurosteroids are generated denovo in the central and peripheral nervous systems and utilize cell surface receptors. Few animal studies indicated synthesis of NS in pituitary. Presence of neurosteroids in human pituitary adenomas(PAs) has yet to be assessed. This is preliminary data of an ongoing study. Seventyseven specimens from huma...